WEBVTT

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(soft music)

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Welcome to "Hadley Presents".

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I'm your host, Ricky Enger inviting you to sit back, relax,

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and enjoy a conversation with the experts.

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In this episode, we explore frequently asked questions

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regarding glaucoma.

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And our guests are glaucoma specialist, Dr. Jullia Rosdahl

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of the Duke Eye Center, interviewed

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by Hadley Chief Program Officer, Ed Haines.

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Welcome to the show, both of you.

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Thanks Ricky.

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Thanks Ricky, I'm really excited to be here.

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I'm excited to have you

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because glaucoma is one of those things

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that I actually don't know as much about as I should,

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even though my fiance has glaucoma

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and sometimes I ask him things

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and he tells me what he knows.

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But I think that I'm going

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to learn a lot more from our conversation today.

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Before we jump into that though, I want

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to know a little about each of you.

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Just tell the audience a bit

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about who you are and what you do.

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Let's start with you, Ed.

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Well, I'm Ed Haines.

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I'm the Chief program officer at Hadley.

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I've been with Hadley about 15 years,

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but I've spent the majority

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of my career in the field working with older adults

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with vision loss, so I've had a lot

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of clients over the years with glaucoma, so I'm thrilled

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to be able to talk to Dr. Al today.

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Fantastic and Dr. Rosdahl,

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how about you, tell us a bit about yourself,

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and I'm always curious

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about how people choose the careers that they do.

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So just tell us a bit about you

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and what made you decide to become a glaucoma specialist.

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Well, thank you.

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So as you noted in the intro,

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I'm a glaucoma specialist at the Duke Eye Center

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in Durham, North Carolina.

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And in additions to seeing patients with glaucoma

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and prescribing eyedrops and doing lasers

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and surgery, I also teach medical students

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and ophthalmology residents,

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and I'm involved in some research as well.

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I lead our wellness program at the Eye Center

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and I serve on some national organizations,

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including the National Eye Health Education Program,

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also called NEHEP,

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and that's part of the National Eye Institute.

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And that's actually where I learned about Hadley

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and the great work that you're doing

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for people with vision loss.

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So I think that's how I was able to connect

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and be a part of this program today.

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You also asked about why I chose glaucoma as a specialty,

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and I really enjoy telling this story.

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When I was in medical school, I did a combined program

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where I earned both a PhD and an MD.

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And yes, my parents did wonder if I

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ever would finish school, but I eventually did.

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And in my PhD I studied how the neurons in the eye,

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the retinal ganglion cells, how they developed

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and made connections in the brain.

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And that led me to the specialty of ophthalmology.

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And then the choice of glaucoma wasn't a choice at all at

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that point because in glaucoma, the neurons that die

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and cause vision loss, those are the retinal ganglion cells.

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And so now every day as a glaucoma specialist,

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my job is really to help people save their vision

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by saving those retinal ganglion cells.

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That is very cool.

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I love hearing about how people got to where they are.

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It's always fascinating story.

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So I'm looking forward

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to learning a bit more about glaucoma

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and so I'm going to sit back

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and just take in the knowledge from both of you.

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So with that, I'm going to turn it over to Ed.

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I know you have some great questions, Ed.

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Well, thanks Ricky.

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Dr. Rosdahl, I wonder if we could just start

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with the basics.

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If you could just tell us what is glaucoma

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and what are maybe some

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of the common risk factors associated with glaucoma?

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So glaucoma is actually

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a group of eye diseases.

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And what they have in common is that the optic nerve,

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which is the cable that connects the eye to the brain,

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it's when that optic nerve becomes thinned out

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because of those neurons, those retinal ganglion cells

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that I mentioned before, of those neurons dying.

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So when the nerve dies off like that, people lose vision

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and it usually affects their peripheral

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or side vision first in glaucoma.

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The most common type of glaucoma in the United States

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is primary open-angle glaucoma.

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And one of the main problems that we have with glaucoma is

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that people have it and they don't know it

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because the vision loss happens really slowly,

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so they don't even notice that it's starting.

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And once you lose vision from glaucoma, really any type

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of glaucoma, not just primary open-angle glaucoma,

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we can't get that vision back.

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So early detection

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and diagnosing glaucoma early is really important

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for saving sight.

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You asked about risk factors.

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So they include having a family history of glaucoma.

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So people in your family, brothers, sisters, aunts, uncles,

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grandparents, and parents.

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Older age is an important risk factor for glaucoma too.

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And actually Black race

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and Hispanic ethnicity are risk factors,

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although a lot of white people can get glaucoma too.

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So don't think that you shouldn't get glaucoma testing

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or screening if you are white.

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What's the typical journey of a patient

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between the time they're diagnosed

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and they actually see you as a glaucoma specialist?

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What's the average scenario that a patient experiences?

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So I would say the scenario that

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we hope for is

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that people are going along in their regular lives

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and they're getting regular complete eye exams

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with their local eye doctors.

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And that local eye doctor recognizes some early sign,

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maybe the eye pressure is a little elevated

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or maybe the optic nerve looks a little suspicious,

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or family history is noted.

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And that savvy local eye doctor either does some

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of the glaucoma testing themselves

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or refers them to someone like me as a glaucoma specialist.

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And then I see them, we do

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what we call a glaucoma evaluation,

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which is a pretty lengthy visit in clinic

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where they get a lot of special testing

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and an in-depth eye exam.

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And we ferret out whether they do have glaucoma

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or just some risk factors that need to be followed.

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So that's the scenario that we hope

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for where the disease is diagnosed early

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before really any vision loss has occurred.

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And we can start treatment early and prevent vision loss.

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So we also get referrals

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for help in managing patients

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who've already sustained vision loss from glaucoma

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or already have advanced glaucoma.

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And sometimes the reasons that they come to us are

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because they need surgery

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or they need some additional treatment that

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that local eye doctor is not able to provide.

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So there are lots of different ways that patients come

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to see a glaucoma specialist,

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but we always hope that they're coming early enough

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where we can save vision.

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And that frequently is the case.

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Actually, most people who are diagnosed with glaucoma

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and treated for glaucoma don't go blind from it.

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And that actually was gonna be my next question.

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I was just gonna ask,

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does you know glaucoma always result

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in some vision loss or blindness?

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Can people with the right kind

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of treatment prevent having any vision loss at all?

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Oh, that's a great question.

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So it is possible for someone to have glaucoma

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and not lose any vision from it.

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The earliest stage of glaucoma is when there is just changes

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to their optic nerve,

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but we're not able to pick up any losses

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in their peripheral vision

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even with automated computerized visual field testing,

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that would be mild glaucoma based on the American Academy

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of Ophthalmology Preferred Practice Patterns,

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but often people, even with mild to moderate glaucoma,

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where we can identify peripheral field defects

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with the computerized automated

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visual field testing, even in those patients,

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often we can pick up those areas

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of vision loss, but they are not noticing it.

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And so those patients too, with treatments started,

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they can really not have vision loss

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that's affecting their quality of life.

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And before we talk about treatments, is it possible

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that the vision loss resulting from glaucoma

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can ever be reversed?

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Or is it a permanent loss of vision?

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So it is a permanent loss of vision

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with the treatments

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that we have at this point, I am very hopeful

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that we will have treatments in the future

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that reverse vision loss from glaucoma,

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but at this point, that vision loss occurs from the death

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of those retinal ganglion cells.

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And we don't have ways yet to renew

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or replace or really recharge

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or regenerate those nerves at this time.

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So it is unfortunately a permanent loss of vision.

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And what are normally the kinds of treatments

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that you prescribe for folks with glaucoma?

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So the main treatment for glaucoma is

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to lower eye pressure.

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And we have a lot of different ways to do it.

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Typically we'll start with eye drop medications

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or a laser treatment to the drain of the eye.

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And then there are also surgical treatments

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that we typically reserve for cases

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where we cannot control the glaucoma with the drops or laser

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or where those treatments are just not effective

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or not possible.

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For example, a patient who has a lot

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of eye drop allergies cannot tolerate any of the drops,

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then surgery might be considered

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for a more mild case as well.

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And I know with eyedrops, I've worked with people

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that are not necessarily as conscientious about compliances,

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maybe they should be.

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So how important is it that the person follow through

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with your exact prescription

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and your instructions for medication?

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Oh, I'm so glad that you brought

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up the topic of adherence

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to treatment regimens.

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It's really, really important

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that patients follow those eye drop treatment regimens.

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I like to say to my patient,

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"This eye drop is a very powerful way to lower eye pressure,

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but it does not work if it is sitting in the bottle,

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it needs to go into your eye."

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There are a lot of different types of eye drops

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that we prescribe.

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And so the regimens can vary quite a bit

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and they also can be quite complex.

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And so I certainly understand when patients have trouble

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adhering to these regimens.

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I would say the most simple one would be a

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once a day eye drop that you might use at bedtime.

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But sometimes we have patients on three

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or even four eye drop medications.

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Some of them need to be dosed two

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or even three times per day.

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And it's quite a feat getting them all in

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at the right times.

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But it's really quite, important those eye drops

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lower eye pressure for a certain amount of time

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after they're instilled,

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and then that eye pressure will go back up once

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that eye drop medication has kind of worn off.

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And so that next dose is timed to really maintain

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that lower eye pressure.

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And we think that maintaining a lower eye pressure

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and really keeping it low without those kind

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of big fluctuations can really help protect the optic nerve,

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help preserve that site.

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Are there any kind of,

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00:12:03.683 --> 00:12:04.516
I think I've had someone tell me

262
00:12:05.550 --> 00:12:07.080
that there's some lifestyle changes

263
00:12:07.080 --> 00:12:08.970
that maybe people need to be aware of too.

264
00:12:08.970 --> 00:12:12.210
Like I think someone told me inverted yoga positions

265
00:12:12.210 --> 00:12:15.030
for instance, people are advised against those

266
00:12:15.030 --> 00:12:16.140
kinds of activities.

267
00:12:16.140 --> 00:12:19.320
Do you recommend lifestyle changes to go with medication

268
00:12:19.320 --> 00:12:21.600
or is that dependent on the individual?

269
00:12:21.600 --> 00:12:24.566
I would say that most patients probably don't

270
00:12:24.566 --> 00:12:29.280
need any particularly extreme lifestyle modifications.

271
00:12:29.280 --> 00:12:31.620
However, if I do have a patient

272
00:12:31.620 --> 00:12:34.950
who is progressing despite a regimen

273
00:12:34.950 --> 00:12:37.140
that we think really should be adequate,

274
00:12:37.140 --> 00:12:39.570
or a patient who's really motivated

275
00:12:39.570 --> 00:12:43.140
to do every single possible thing they can think of

276
00:12:43.140 --> 00:12:44.250
to prevent their disease,

277
00:12:44.250 --> 00:12:47.370
then we do talk about lifestyle modifications.

278
00:12:47.370 --> 00:12:50.310
And the things that I talk about with patients include

279
00:12:50.310 --> 00:12:53.010
that yoga concern that you brought up.

280
00:12:53.010 --> 00:12:54.180
We do think

281
00:12:54.180 --> 00:12:58.980
that prolonged head down postures like doing headstands,

282
00:12:58.980 --> 00:13:03.270
that that can increase the pressure in the eye just

283
00:13:03.270 --> 00:13:08.270
from that elevated venous pressure, tight neck ties as well.

284
00:13:08.550 --> 00:13:13.110
And interestingly, prolonged wind instrument playing

285
00:13:13.110 --> 00:13:15.780
where you're blowing against a reed

286
00:13:15.780 --> 00:13:18.450
and again, kind of increased pressure in your head

287
00:13:18.450 --> 00:13:22.410
from those prolonged periods of kind of holding your breath

288
00:13:22.410 --> 00:13:24.600
and breathing against that wind instrument.

289
00:13:24.600 --> 00:13:28.890
We think that those might potentially result

290
00:13:28.890 --> 00:13:32.460
in some potential progression of glaucoma.

291
00:13:32.460 --> 00:13:36.180
I would say that I don't like to tell people not to do yoga,

292
00:13:36.180 --> 00:13:39.840
however, because I think that it's a really good way

293
00:13:39.840 --> 00:13:44.760
to relax, recharge, and good for your health.

294
00:13:44.760 --> 00:13:47.490
So it's really those prolonged head down postures.

295
00:13:47.490 --> 00:13:50.250
There are a couple other lifestyle modifications

296
00:13:50.250 --> 00:13:51.990
too to consider.

297
00:13:51.990 --> 00:13:55.260
One of them is to eat a diet with a lot

298
00:13:55.260 --> 00:13:58.620
of leafy green vegetables with antioxidants.

299
00:13:58.620 --> 00:14:01.980
We think that might help the optic nerve in glaucoma.

300
00:14:01.980 --> 00:14:03.900
Healthy lifestyle in general

301
00:14:03.900 --> 00:14:06.330
with a heart healthy diet

302
00:14:06.330 --> 00:14:10.110
with lots of vegetables, fruits, whole grains,

303
00:14:10.110 --> 00:14:13.140
and lean proteins, getting some exercise,

304
00:14:13.140 --> 00:14:16.350
getting enough sleep, having healthy relationships

305
00:14:16.350 --> 00:14:17.850
with loved ones,

306
00:14:17.850 --> 00:14:20.070
those are things that are good for your overall health

307
00:14:20.070 --> 00:14:22.590
and so they're gonna be good for your eyes.

308
00:14:22.590 --> 00:14:25.020
And then there's one that's kind of interesting

309
00:14:25.020 --> 00:14:29.490
around sleeping with a wedge type pillow,

310
00:14:29.490 --> 00:14:33.330
having your head elevated around 30 degrees.

311
00:14:33.330 --> 00:14:34.830
That's something that's been shown

312
00:14:34.830 --> 00:14:38.010
to decrease progression in really advanced glaucoma

313
00:14:38.010 --> 00:14:39.447
in some studies as well.

314
00:14:39.447 --> 00:14:41.370
And so that's something else that I'll bring up

315
00:14:41.370 --> 00:14:44.910
with a patient who might be progressing despite

316
00:14:44.910 --> 00:14:47.940
what we think is adequate pressure control.

317
00:14:47.940 --> 00:14:51.630
Now if people are adhering to their treatment

318
00:14:51.630 --> 00:14:54.780
and they're taking all their drops the way they should,

319
00:14:54.780 --> 00:14:57.180
does glaucoma ever just stop?

320
00:14:57.180 --> 00:14:58.013
Does it go away?

321
00:14:58.013 --> 00:14:59.040
Or do they have to get treated

322
00:14:59.040 --> 00:15:01.650
for this condition for the rest of their lives?

323
00:15:01.650 --> 00:15:03.990
That is a really common question, Ed.

324
00:15:03.990 --> 00:15:05.640
I'm glad that you asked that.

325
00:15:05.640 --> 00:15:09.840
Glaucoma is a lifelong condition, once you have it,

326
00:15:09.840 --> 00:15:11.610
we have lots of good treatments,

327
00:15:11.610 --> 00:15:13.650
but we really don't have a cure.

328
00:15:13.650 --> 00:15:15.780
And so typically patients do have it

329
00:15:15.780 --> 00:15:17.680
for the rest of their lives.

330
00:15:17.680 --> 00:15:21.090
However, treatments change, responses

331
00:15:21.090 --> 00:15:22.920
to treatments change as well.

332
00:15:22.920 --> 00:15:26.040
And so it is something that has to be monitored

333
00:15:26.040 --> 00:15:27.870
for the patient's life.

334
00:15:27.870 --> 00:15:32.870
Often though it is controlled and people do not go blind.

335
00:15:33.142 --> 00:15:36.060
If I'm diagnosed with glaucoma, do I have

336
00:15:36.060 --> 00:15:38.430
to start being concerned about my kids

337
00:15:38.430 --> 00:15:40.722
or potential grandkids?

338
00:15:40.722 --> 00:15:43.620
Is genetic counseling involved with this?

339
00:15:43.620 --> 00:15:45.090
When would my children, for instance,

340
00:15:45.090 --> 00:15:47.400
need to start being tested for glaucoma

341
00:15:47.400 --> 00:15:48.930
if I've been diagnosed?

342
00:15:48.930 --> 00:15:51.510
Well, glaucoma does run in families,

343
00:15:51.510 --> 00:15:54.330
and so it's a really good idea if you are diagnosed

344
00:15:54.330 --> 00:15:56.970
with glaucoma that you let blood relatives know

345
00:15:56.970 --> 00:15:58.770
about that diagnosis.

346
00:15:58.770 --> 00:16:01.050
And they don't necessarily need to run out

347
00:16:01.050 --> 00:16:03.510
and see a glaucoma specialist right away.

348
00:16:03.510 --> 00:16:07.320
But they should have complete eye exams on a regular basis.

349
00:16:07.320 --> 00:16:09.840
And when they see their eye doctor,

350
00:16:09.840 --> 00:16:13.500
they should tell them about that family history of glaucoma.

351
00:16:13.500 --> 00:16:16.050
And if the doctor sees anything of concern,

352
00:16:16.050 --> 00:16:18.960
more testings needed, like a visual field test

353
00:16:18.960 --> 00:16:21.750
or a computerized picture of the optic nerve,

354
00:16:21.750 --> 00:16:24.690
then they might need to see a glaucoma specialist.

355
00:16:24.690 --> 00:16:26.610
So I would say if you had children

356
00:16:26.610 --> 00:16:29.820
and you were diagnosed with glaucoma, then I'd recommend

357
00:16:29.820 --> 00:16:33.120
that they have a complete dilated eye exam

358
00:16:33.120 --> 00:16:36.900
with a local eye doctor if they haven't had one recently

359
00:16:36.900 --> 00:16:41.250
and to let the doctor know about your diagnosis.

360
00:16:41.250 --> 00:16:44.760
Are there any kinds of just sort of misapprehensions

361
00:16:44.760 --> 00:16:47.370
and false knowledge out there about glaucoma

362
00:16:47.370 --> 00:16:50.310
and treatment that you see that patients come to you with

363
00:16:50.310 --> 00:16:51.990
that you'd like to dispel?

364
00:16:51.990 --> 00:16:54.600
Well, the most important one, I think is one

365
00:16:54.600 --> 00:16:58.590
that we've touched on already, that fear of blindness.

366
00:16:58.590 --> 00:17:01.470
When people first get the diagnosis, they think that,

367
00:17:01.470 --> 00:17:05.100
oh my gosh, I will be going blind.

368
00:17:05.100 --> 00:17:07.380
But like we discussed, most people who are treated

369
00:17:07.380 --> 00:17:09.030
for glaucoma don't go blind.

370
00:17:09.030 --> 00:17:12.000
So the message should really be one of hope.

371
00:17:12.000 --> 00:17:15.630
The biggest misapprehension about glaucoma treatment,

372
00:17:15.630 --> 00:17:18.210
I would say, is about the effects of treatment.

373
00:17:18.210 --> 00:17:19.620
Most people expect

374
00:17:19.620 --> 00:17:23.100
that glaucoma eyedrops will make their eyes feel better

375
00:17:23.100 --> 00:17:26.970
or help them to see better, but that really isn't the case.

376
00:17:26.970 --> 00:17:30.120
Eyedrops for glaucoma help to lower the eye pressure

377
00:17:30.120 --> 00:17:32.700
to prevent future vision loss.

378
00:17:32.700 --> 00:17:34.290
So they help keep your vision,

379
00:17:34.290 --> 00:17:36.150
but they don't make vision better.

380
00:17:36.150 --> 00:17:38.850
And they can have some side effects.

381
00:17:38.850 --> 00:17:42.360
Most of them are manageable, people do great on their drops,

382
00:17:42.360 --> 00:17:45.330
but there can be some stinging or redness.

383
00:17:45.330 --> 00:17:48.930
And sometimes we do need to even stop or change drops

384
00:17:48.930 --> 00:17:50.820
because of side effects.

385
00:17:50.820 --> 00:17:54.690
So that misapprehension about the effects of treatment,

386
00:17:54.690 --> 00:17:57.660
that's one that I'd like people to know about too.

387
00:17:57.660 --> 00:18:00.090
And once folks start seeing you

388
00:18:00.090 --> 00:18:02.760
as their glaucoma specialist, do they still need

389
00:18:02.760 --> 00:18:04.950
to see their local optometrist

390
00:18:04.950 --> 00:18:07.440
or their local ophthalmologist as well?

391
00:18:07.440 --> 00:18:09.720
Or do you kind of handle their care,

392
00:18:09.720 --> 00:18:12.570
their primary eye care from that point forward?

393
00:18:12.570 --> 00:18:13.403
So optometrists and the

394
00:18:13.403 --> 00:18:14.236
comprehensive ophthalmologists

395
00:18:16.590 --> 00:18:19.080
are really important partners for us.

396
00:18:19.080 --> 00:18:21.780
I would say some of my patients do just see me

397
00:18:21.780 --> 00:18:25.830
for their eye care and kind of transfer things over to me.

398
00:18:25.830 --> 00:18:29.640
Many of them have other eye problems like dry eye

399
00:18:29.640 --> 00:18:32.370
or glasses, a need for contacts,

400
00:18:32.370 --> 00:18:34.500
and those are things that the optometrist

401
00:18:34.500 --> 00:18:36.900
or that comprehensive doctor is helping with.

402
00:18:36.900 --> 00:18:41.900
And so they'll still see them for those reasons.

403
00:18:41.910 --> 00:18:45.630
And some patients have to travel quite a distance to see me.

404
00:18:45.630 --> 00:18:47.220
And so we will partner with

405
00:18:47.220 --> 00:18:49.980
that local eye doctor, for example,

406
00:18:49.980 --> 00:18:52.650
they'll get their eye pressure checks every three

407
00:18:52.650 --> 00:18:54.030
or four months locally

408
00:18:54.030 --> 00:18:56.370
and then come to see me once a year

409
00:18:56.370 --> 00:18:59.400
for the visual field testing, the optic nerve imaging

410
00:18:59.400 --> 00:19:01.560
and the dilated exam as long

411
00:19:01.560 --> 00:19:04.440
as everything's been stable at those interim visits

412
00:19:04.440 --> 00:19:06.060
with their local doctor.

413
00:19:06.060 --> 00:19:07.260
Oh, that makes perfect sense.

414
00:19:07.260 --> 00:19:11.430
And this is a question I was interested in asking you.

415
00:19:11.430 --> 00:19:13.800
I've worked in the past with a lot of people

416
00:19:13.800 --> 00:19:16.740
with age-related macular degeneration

417
00:19:16.740 --> 00:19:19.950
and the dry type, particularly now that they've been told,

418
00:19:19.950 --> 00:19:22.170
well, there's just really nothing that can be done.

419
00:19:22.170 --> 00:19:23.790
And I'll visit them.

420
00:19:23.790 --> 00:19:25.500
I'll notice for instance, on their chart

421
00:19:25.500 --> 00:19:27.330
that they also have glaucoma.

422
00:19:27.330 --> 00:19:30.090
And I'll say, "Have you seen a glaucoma specialist?"

423
00:19:30.090 --> 00:19:32.040
And they commonly tell me, "Well,

424
00:19:32.040 --> 00:19:34.650
I know nothing can be done about my vision,

425
00:19:34.650 --> 00:19:36.090
so why should I bother?"

426
00:19:36.090 --> 00:19:39.270
What would you say to to patients like that?

427
00:19:39.270 --> 00:19:41.670
So I often have patients

428
00:19:41.670 --> 00:19:45.690
who have both macular degeneration and glaucoma,

429
00:19:45.690 --> 00:19:48.240
and I partner with my retina colleagues

430
00:19:48.240 --> 00:19:49.920
to care for those patients.

431
00:19:49.920 --> 00:19:51.990
And I think these are some of the patients

432
00:19:51.990 --> 00:19:56.160
where glaucoma care is really so important.

433
00:19:56.160 --> 00:19:59.550
Patients with macular degeneration typically have losses

434
00:19:59.550 --> 00:20:01.200
in their central vision,

435
00:20:01.200 --> 00:20:03.870
but their peripheral vision might still be intact

436
00:20:03.870 --> 00:20:06.930
and be helping them with mobility

437
00:20:06.930 --> 00:20:09.810
and seeing to do a lot of the things that they need

438
00:20:09.810 --> 00:20:12.000
to do to live their lives.

439
00:20:12.000 --> 00:20:15.150
And so the glaucoma care is really essential

440
00:20:15.150 --> 00:20:19.080
to help them preserve that functional peripheral vision

441
00:20:19.080 --> 00:20:22.410
that's allowing them to live the lives that they want

442
00:20:22.410 --> 00:20:24.720
to live like they are.

443
00:20:24.720 --> 00:20:27.900
And so that glaucoma care is really essential.

444
00:20:27.900 --> 00:20:28.980
Okay, great advice.

445
00:20:28.980 --> 00:20:32.340
I know it's scary how common I've that is

446
00:20:32.340 --> 00:20:34.440
and how much I've heard that though.

447
00:20:34.440 --> 00:20:38.100
Are there any treatments on the horizon for glaucoma

448
00:20:38.100 --> 00:20:40.560
that show promise that might be more effective than

449
00:20:40.560 --> 00:20:42.090
what you're using now?

450
00:20:42.090 --> 00:20:44.070
Well, there is a lot happening

451
00:20:44.070 --> 00:20:45.960
in glaucoma treatment right now.

452
00:20:45.960 --> 00:20:48.990
It's been a really exciting time for us.

453
00:20:48.990 --> 00:20:50.370
In the last couple of years,

454
00:20:50.370 --> 00:20:55.370
we had two new medications approved for glaucoma treatment,

455
00:20:55.560 --> 00:20:59.430
and the two mechanisms of action are new as well.

456
00:20:59.430 --> 00:21:02.970
So they're quite additive to the eye drops

457
00:21:02.970 --> 00:21:04.590
that we currently have.

458
00:21:04.590 --> 00:21:07.080
They are considered second line,

459
00:21:07.080 --> 00:21:10.230
however, so they're not necessarily better than

460
00:21:10.230 --> 00:21:14.190
what we have, but they can be added in a really powerful way

461
00:21:14.190 --> 00:21:16.260
to help us with our patients.

462
00:21:16.260 --> 00:21:20.370
And in 2020, just in this past year, a new way

463
00:21:20.370 --> 00:21:25.290
of delivering glaucoma medications was approved by the FDA,

464
00:21:25.290 --> 00:21:26.670
and it's an implant

465
00:21:26.670 --> 00:21:30.210
that we can inject right into the front part of the eye.

466
00:21:30.210 --> 00:21:34.530
It's tiny tinier than the letter I on a dime.

467
00:21:34.530 --> 00:21:38.160
And then that medication sits in the front of the eye

468
00:21:38.160 --> 00:21:40.530
and elutes over a period of four

469
00:21:40.530 --> 00:21:42.330
to six months before wearing off.

470
00:21:42.330 --> 00:21:46.950
So that's a really exciting development in medications.

471
00:21:46.950 --> 00:21:48.840
And then there has also been a lot

472
00:21:48.840 --> 00:21:52.950
of focus on developing safer surgeries for glaucoma

473
00:21:52.950 --> 00:21:54.240
and advances in what are

474
00:21:54.240 --> 00:21:58.590
called minimally invasive glaucoma surgeries or MIGS.

475
00:21:58.590 --> 00:22:01.530
However, they really do seem best for people with mild

476
00:22:01.530 --> 00:22:05.250
to moderate glaucoma who also have a cataract that's ready

477
00:22:05.250 --> 00:22:09.000
for cataract surgery and want to be on fewer eyedrops.

478
00:22:09.000 --> 00:22:13.560
So we still really need safer alternatives for our patients

479
00:22:13.560 --> 00:22:15.240
with more advanced glaucoma

480
00:22:15.240 --> 00:22:17.550
who really need those lower pressures.

481
00:22:17.550 --> 00:22:20.820
The MIGS surgeries aren't quite there for us

482
00:22:20.820 --> 00:22:22.290
for those patients yet.

483
00:22:22.290 --> 00:22:25.560
And we still need those nerve regenerative therapies

484
00:22:25.560 --> 00:22:28.710
to bring vision back for our patients.

485
00:22:28.710 --> 00:22:30.990
But we have a lot of scientists

486
00:22:30.990 --> 00:22:34.380
and researchers around the world who are working hard

487
00:22:34.380 --> 00:22:36.420
to develop those treatments for our patients.

488
00:22:36.420 --> 00:22:39.150
But unfortunately, we're still waiting for those.

489
00:22:39.150 --> 00:22:41.370
Well Dr. Rosdahl, you've talked about treatments

490
00:22:41.370 --> 00:22:43.680
and I just wanted to ask you one quick question

491
00:22:43.680 --> 00:22:46.230
that's come up with folks that I've worked with in the past,

492
00:22:46.230 --> 00:22:49.440
particularly folks who may not have the insurance

493
00:22:49.440 --> 00:22:52.230
or the money to pay for eyedrops, et cetera,

494
00:22:52.230 --> 00:22:54.090
and that's medical marijuana

495
00:22:54.090 --> 00:22:57.270
and how efficacious is medical marijuana

496
00:22:57.270 --> 00:22:58.950
in treating glaucoma

497
00:22:58.950 --> 00:23:01.590
and should people depend on that as opposed

498
00:23:01.590 --> 00:23:03.540
to actually seeking out treatments

499
00:23:03.540 --> 00:23:05.460
from a glaucoma specialist?

500
00:23:05.460 --> 00:23:06.930
You know Ed, I'm glad you asked that

501
00:23:06.930 --> 00:23:10.230
because I think a lot of patients might be afraid

502
00:23:10.230 --> 00:23:11.640
to ask that question.

503
00:23:11.640 --> 00:23:14.040
But it is a really important question

504
00:23:14.040 --> 00:23:17.280
because I really would ask

505
00:23:17.280 --> 00:23:21.720
that patients not use marijuana for treatment of glaucoma

506
00:23:21.720 --> 00:23:24.450
because it has not been shown to be effective

507
00:23:24.450 --> 00:23:29.070
or safe for treating glaucoma and preventing vision loss.

508
00:23:29.070 --> 00:23:33.720
There's certainly anecdotal accounts of pressure lowering

509
00:23:33.720 --> 00:23:37.080
and potentially different parts of marijuana,

510
00:23:37.080 --> 00:23:41.010
different components that might eventually be part

511
00:23:41.010 --> 00:23:45.690
of an approved treatment for glaucoma, but not at this time.

512
00:23:45.690 --> 00:23:49.530
And so it really isn't a good way to prevent vision loss.

513
00:23:49.530 --> 00:23:50.940
I hope, though,

514
00:23:50.940 --> 00:23:55.290
that we will have marijuana based eye drops in the future

515
00:23:55.290 --> 00:23:58.980
because I think that that is going to really boost adherence

516
00:23:58.980 --> 00:24:03.030
for glaucoma treatment in the future.

517
00:24:03.030 --> 00:24:04.830
But at this point,

518
00:24:04.830 --> 00:24:09.830
medical marijuana is not an approved treatment for glaucoma.

519
00:24:09.960 --> 00:24:12.180
Eyedrops, laser surgery,

520
00:24:12.180 --> 00:24:14.280
those are the things that we know work.

521
00:24:14.280 --> 00:24:17.040
If patients are struggling with the cost

522
00:24:17.040 --> 00:24:20.160
of their glaucoma care, there are actually a lot

523
00:24:20.160 --> 00:24:23.850
of great programs that a lot of the drug companies offer

524
00:24:23.850 --> 00:24:27.480
to help patients get the medications that they need.

525
00:24:27.480 --> 00:24:29.220
And so I'd encourage those folks

526
00:24:29.220 --> 00:24:32.220
to ask their doctor about different programs

527
00:24:32.220 --> 00:24:34.980
that these pharmaceutical companies have available

528
00:24:34.980 --> 00:24:37.620
for patients who can't afford them.

529
00:24:37.620 --> 00:24:38.970
Well, that's terrific information

530
00:24:38.970 --> 00:24:40.350
'cause I know that is a concern.

531
00:24:40.350 --> 00:24:42.960
So thanks very much and I'm glad I asked the question.

532
00:24:42.960 --> 00:24:43.793
Yeah, that's a great knowledge to

533
00:24:43.793 --> 00:24:44.626
have as is all of this.

534
00:24:46.800 --> 00:24:49.980
I've actually learned quite a bit,

535
00:24:49.980 --> 00:24:54.330
even with some limited knowledge of glaucoma,

536
00:24:54.330 --> 00:24:56.220
I've certainly added to that today.

537
00:24:56.220 --> 00:25:00.210
So I certainly appreciate the opportunity to sit back

538
00:25:00.210 --> 00:25:03.810
and listen as you all discussed this.

539
00:25:03.810 --> 00:25:07.590
As we're wrapping up here, just wanna ask,

540
00:25:07.590 --> 00:25:11.670
are there places that you would recommend either of you,

541
00:25:11.670 --> 00:25:13.140
either Ed or Dr. Rosdahl,

542
00:25:13.140 --> 00:25:16.680
places that patients can go if they want

543
00:25:16.680 --> 00:25:21.510
to read a bit more about glaucoma, whether it's treatment

544
00:25:21.510 --> 00:25:24.598
or perhaps if they're looking for a glaucoma specialist,

545
00:25:24.598 --> 00:25:26.700
places that they can go just

546
00:25:26.700 --> 00:25:29.340
to do some of their own research?

547
00:25:29.340 --> 00:25:31.920
So the websites that I recommend

548
00:25:31.920 --> 00:25:36.300
for learning about glaucoma include the American Academy

549
00:25:36.300 --> 00:25:39.720
of Ophthalmology Patient Education website.

550
00:25:39.720 --> 00:25:43.050
That is called eyesmart.org,

551
00:25:43.050 --> 00:25:46.620
E-Y-E-S-M-A-R-T.org.

552
00:25:46.620 --> 00:25:49.350
It is a great resource for patients.

553
00:25:49.350 --> 00:25:52.650
The National Eye Institute also has a lot

554
00:25:52.650 --> 00:25:54.990
of great information about glaucoma

555
00:25:54.990 --> 00:25:58.770
and some of the more scientific advancements

556
00:25:58.770 --> 00:26:00.600
that are going on right now.

557
00:26:00.600 --> 00:26:03.090
And if you're looking for a glaucoma specialist,

558
00:26:03.090 --> 00:26:05.190
of course the best way is gonna be

559
00:26:05.190 --> 00:26:08.280
to ask your local eye doctor for a recommendation

560
00:26:08.280 --> 00:26:11.700
for someone that they work well with and that they know.

561
00:26:11.700 --> 00:26:12.810
But if you're online

562
00:26:12.810 --> 00:26:14.610
and you're looking for someone,

563
00:26:14.610 --> 00:26:17.310
the American Glaucoma Society,

564
00:26:17.310 --> 00:26:20.850
or AGS, we maintain a list

565
00:26:20.850 --> 00:26:23.640
of fellowship trained glaucoma specialists

566
00:26:23.640 --> 00:26:27.390
in the United States and patients can go on that site

567
00:26:27.390 --> 00:26:29.820
and search by zip code to look

568
00:26:29.820 --> 00:26:33.120
for a fellowship trained glaucoma specialists.

569
00:26:33.120 --> 00:26:35.670
Fantastic and we'll have all

570
00:26:35.670 --> 00:26:38.700
of those resources in our show notes.

571
00:26:38.700 --> 00:26:40.290
I wanna thank you both so much

572
00:26:40.290 --> 00:26:42.240
for spending a little time with us today.

573
00:26:42.240 --> 00:26:44.880
I'm so glad and I am very appreciative

574
00:26:44.880 --> 00:26:46.740
of the information that you've shared.

575
00:26:46.740 --> 00:26:48.150
Oh, you're welcome, it was a pleasure.

576
00:26:48.150 --> 00:26:48.983
It's been my pleasure,

577
00:26:48.983 --> 00:26:49.816
Ricky and Ed, thank you so much.

578
00:26:51.780 --> 00:26:52.613
Thank you.

579
00:26:53.700 --> 00:26:55.380
Got something to say?

580
00:26:55.380 --> 00:26:59.130
Share your thoughts about this episode of "Hadley Presents",

581
00:26:59.130 --> 00:27:01.950
or make suggestions for future episodes.

582
00:27:01.950 --> 00:27:03.720
We'd love to hear from you.

583
00:27:03.720 --> 00:27:08.130
Send us an email at podcast@hadley.edu.

584
00:27:08.130 --> 00:27:13.130
That's P-O-D-C-A-S-T@hadley.edu.

585
00:27:13.230 --> 00:27:17.523
Or leave us a message at 847-784-2870.

586
00:27:20.010 --> 00:27:21.885
Thanks for listening.

587
00:27:21.885 --> 00:27:24.385
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